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1

Regulation of drug transporter expression and function in the placenta

Staud, Frantisek, Ceckova, Martina

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2015

Language:

english

File:

PDF, 732 KB

english, 2015

2

P-glycoprotein in the placenta: Expression, localization, regulation and function

Martina Ceckova-Novotna, Petr Pavek, Frantisek Staud

Journal:

Reproductive Toxicology

Year:

2006

Language:

english

File:

PDF, 1.07 MB

english, 2006

3

Serotonin homeostasis in the maternoâfetal interface at term: role of transporters (SERT/SLC6A4 and OCT3/SLC22A3) and monoamine oxidase A (MAOâA) in uptake and degradation of serotonin by human and rat term placenta

Karahoda, Rona, Horackova, Hana, Kastner, Petr, Matthios, Andreas, Cerveny, Lukas, Kucera, Radim, Kacerovsky, Marian, Tebbens, Jurjen Duintjer, Bonnin, Alexandre, Abad, Cilia, Staud, Frantisek

Journal:

Acta Physiologica

Year:

2020

File:

PDF, 45.07 MB

2020

4

Amiodarone modulates pharmacokinetics of low-dose methotrexate in rats

Leos Fuksa, Eva Brcakova, Jolana Cermanova, Milos Hroch, Jaroslav Chladek, Gabriela Kolouchova, Jana Malakova, Jirina Martinkova, Frantisek Staud, Stanislav Micuda

Journal:

Biopharmaceutics & Drug Disposition

Year:

2008

Language:

english

File:

PDF, 128 KB

english, 2008

5

Synthesis and antimicrobial evaluation of new 2-substituted 5,7-di-tert-butylbenzoxazoles

Jarmila Vinsova, Katerina Cermakova, Alexandra Tomeckova, Martina Ceckova, Josef Jampilek, Pavel Cermak, Jiri Kunes, Martin Dolezal, Frantisek Staud

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 271 KB

english, 2006

6

Synthesis of pH-sensitive amphotericin B–poly(ethylene glycol) conjugates and study of their controlled release in vitro

Miloš Sedlák, Martin Pravda, Frantisek Staud, Lenka Kubicová, Kateřina Týčová, Karel Ventura

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 211 KB

english, 2007

7

Dexamethasone reduces methotrexate biliary elimination and potentiates its hepatotoxicity in rats

Leos Fuksa, Eva Brcakova, Gabriela Kolouchova, Petra Hirsova, Milos Hroch, Jolana Cermanova, Frantisek Staud, Stanislav Micuda

Journal:

Year:

2010

Language:

english

File:

PDF, 538 KB

english, 2010

8

EXPRESSION AND FUNCTIONAL ACTIVITY OF BREAST CANCER RESISTANCE PROTEIN (BCRP, ABCG2) TRANSPORTER IN THE HUMAN CHORIOCARCINOMA CELL LINE BEWO

Martina Ceckova, Antonin Libra, Petr Pavek, Petr Nachtigal, Marianne Brabec, Renate Fuchs, Frantisek Staud

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2006

Language:

english

File:

PDF, 228 KB

english, 2006

9

MORPHOLOGICAL AND FUNCTIONAL CHANGES IN P-GLYCOPROTEIN DURING DEXAMETHASONE-INDUCED HEPATOMEGALY

Stanislav Micuda, Leos Fuksa, Lucie Mundlova, Jan Osterreicher, Jaroslav Mokry, Jolana Cermanova, Eva Brcakova, Frantisek Staud, Pavla Pokorna, Jirina Martinkova

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2007

Language:

english

File:

PDF, 237 KB

english, 2007

10

Zonation of multidrug resistance-associated protein 2 in rat liver after induction with dexamethasone

Stanislav Micuda, Leos Fuksa, Eva Brcakova, Jan Osterreicher, Jolana Cermanova, Norbert Cibicek, Jaroslav Mokry, Frantisek Staud, Jirina Martinkova

Journal:

Journal of Gastroenterology and Hepatology

Year:

2008

Language:

english

File:

PDF, 265 KB

english, 2008

11

Lack of Interactions between Breast Cancer Resistance Protein (BCRP/ABCG2) and Selected Antiepileptic Agents

Lukas Cerveny, Petr Pavek, Jana Malakova, Frantisek Staud, Zdenek Fendrich

Journal:

Year:

2006

Language:

english

File:

PDF, 292 KB

english, 2006

12

Disposition of radioactivity after injection of liver-targeted proteins labeled with 111In or 125I. Effect of labeling on distribution and excretion of radioactivity in rats

Frantisek Staud, Makiya Nishikawa, Kensuke Morimoto, Yoshinobu Takakura, Mitsuru Hashida

Journal:

Journal of Pharmaceutical Sciences

Year:

1999

Language:

english

File:

PDF, 211 KB

english, 1999

13

P-glycoprotein expression and distribution in the rat placenta during pregnancy

Martina Novotna, Antonin Libra, Martin Kopecky, Petr Pavek, Zdenek Fendrich, Vladimir Semecky, Frantisek Staud

Journal:

Reproductive Toxicology

Year:

2004

Language:

english

File:

PDF, 362 KB

english, 2004

14

Dexamethasone and betamethasone administration during pregnancy affects expression and function of 11β-hydroxysteroid dehydrogenase type 2 in the rat placenta

Zuzana Vackova, Karla Vagnerova, Antonin Libra, Ivan Miksik, Jiri Pacha, Frantisek Staud

Journal:

Reproductive Toxicology

Year:

2009

Language:

english

File:

PDF, 351 KB

english, 2009

15

Transfer of clorazepate and nordiazepam across the umbilically perfused rat term placenta in situ: Comparison with flunitrazepam and diazepam

Petr Pávek, František Štaud, Zdenek Fendrich, Jana Maláková, Vladimír Palicka

Journal:

Year:

1999

Language:

english

File:

PDF, 669 KB

english, 1999

16

Breast cancer resistance protein (BCRP/ABCG2)

Frantisek Staud, Petr Pavek

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2005

Language:

english

File:

PDF, 230 KB

english, 2005

17

Effect of ABCG2 on cytotoxicity of platinum drugs: Interference of EGFP

Martina Ceckova, Zuzana Vackova, Hana Radilova, Antonin Libra, Martin Buncek, Frantisek Staud

Journal:

Toxicology in Vitro

Year:

2008

Language:

english

File:

PDF, 277 KB

english, 2008

18

Liver uptake and hepato-biliary transfer of galactosylated proteins in rats are determined by the extent of galactosylation

Frantisek Staud, Makiya Nishikawa, Yoshinobu Takakura, Mitsuru Hashida

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1999

Language:

english

File:

PDF, 305 KB

english, 1999

19

Pharmacokinetics of Flunitrazepam Transfer Across the Rat Term Placenta

František Štaud, Zdenek Fendrich, Jana Kopecká, Vladimír Palička, Milan Lázniček

Journal:

Journal of Pharmacy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 416 KB

english, 1996

20

Up-regulation of renal Mdr1 and Mrp2 transporters during amiodarone pretreatment in rats

Jolana Cermanova, Leos Fuksa, Eva Brcakova, Milos Hroch, Otto Kucera, Gabriela Kolouchova, Petra Hirsova, Jana Malakova, Frantisek Staud, Jirina Martinkova, Zuzana Cervinkova, Stanislav Micuda

Journal:

Pharmacological Research

Year:

2010

Language:

english

File:

PDF, 364 KB

english, 2010

21

Olomoucine II and purvalanol A inhibit ABCG2 transporter in vitro and in situ and synergistically potentiate cytostatic effect of mitoxantrone

Jakub Hofman, Davoud Ahmadimoghaddam, Lenka Hahnova, Petr Pavek, Martina Ceckova, Frantisek Staud

Journal:

Pharmacological Research

Year:

2012

Language:

english

File:

PDF, 988 KB

english, 2012

22

Role of breast cancer resistance protein (Bcrp/Abcg2) in fetal protection during gestation in rat

Lenka Cygalova, Martina Ceckova, Petr Pavek, Frantisek Staud

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 329 KB

english, 2008

23

Pharmacotherapy in pregnancy; effect of ABC and SLC transporters on drug transport across the placenta and fetal drug exposure

Staud, Frantisek, Cerveny, Lukas, Ceckova, Martina

Journal:

Journal of Drug Targeting

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

24

Transfer of metformin across the rat placenta is mediated by organic cation transporter 3 (OCT3/SLC22A3) and multidrug and toxin extrusion 1 (MATE1/SLC47A1) protein

Ahmadimoghaddam, Davoud, Staud, Frantisek

Journal:

Reproductive Toxicology

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

25

Salicylanilide Acetates: Synthesis and Antibacterial Evaluation

Vinsova, Jarmila, Imramovsky, Ales, Buchta, Vladimir, Ceckova, Martina, Dolezal, Martin, Staud, Frantisek, Jampilek, Josef, Kaustova, Jarmila

Journal:

Year:

2007

Language:

english

File:

PDF, 82 KB

english, 2007

26

Multidrug and toxin extrusion proteins (MATE/SLC47); role in pharmacokinetics

Staud, Frantisek, Cerveny, Lukas, Ahmadimoghaddam, Davoud, Ceckova, Martina

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

27

Fetoprotective activity of breast cancer resistance protein (BCRP, ABCG2): expression and function throughout pregnancy

Hahnova-Cygalova, Lenka, Ceckova, Martina, Staud, Frantisek

Journal:

Drug Metabolism Reviews

Year:

2011

Language:

english

File:

PDF, 943 KB

english, 2011

28

IL-1 receptor blockade alleviates endotoxin-mediated impairment of renal drug excretory functions in rats

Kadova, Zuzana, Dolezelova, Eva, Cermanova, Jolana, Hroch, Milos, Laho, Tomas, Muchova, Lucie, Staud, Frantisek, Vitek, Libor, Mokry, Jaroslav, Chladek, Jaroslav, Havlinova, Zuzana, Holecek, Milan, Mi

Journal:

AJP: Renal Physiology

Year:

2015

Language:

english

File:

PDF, 834 KB

english, 2015

29

Boldine enhances bile production in rats via osmotic and Farnesoid X receptor dependent mechanisms

Cermanova, Jolana, Kadova, Zuzana, Zagorova, Marie, Hroch, Milos, Tomsik, Pavel, Nachtigal, Petr, Kudlackova, Zdenka, Pavek, Petr, Dubecka, Michaela, Ceckova, Martina, Staud, Frantisek, Laho, Tomas, M

Journal:

Toxicology and Applied Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.76 MB

english, 2015

30

Interactions of cyclin-dependent kinase inhibitors AT-7519, flavopiridol and SNS-032 with ABCB1, ABCG2 and ABCC1 transporters and their potential to overcome multidrug resistance in vitro

Cihalova, Daniela, Staud, Frantisek, Ceckova, Martina

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2015

Language:

english

File:

PDF, 866 KB

english, 2015

31

Effect of drug efflux transporters on placental transport of antiretroviral agent abacavir

Neumanova, Zuzana, Cerveny, Lukas, Greenwood, Susan L., Ceckova, Martina, Staud, Frantisek

Journal:

Reproductive Toxicology

Year:

2015

Language:

english

File:

PDF, 959 KB

english, 2015

32

Dinaciclib, a cyclin-dependent kinase inhibitor, is a substrate of human ABCB1 and ABCG2 and an inhibitor of human ABCC1 in vitro

Cihalova, Daniela, Ceckova, Martina, Kucera, Radim, Klimes, Jiri, Staud, Frantisek

Journal:

Biochemical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

33

Role of ABCB1, ABCG2, ABCC2 and ABCC5 transporters in placental passage of zidovudine

Neumanova, Zuzana, Cerveny, Lukas, Ceckova, Martina, Staud, Frantisek

Journal:

Biopharmaceutics & Drug Disposition

Year:

2016

Language:

english

File:

PDF, 557 KB

english, 2016

34

Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters

Reznicek, Josef, Ceckova, Martina, Cerveny, Lukas, Müller, Fabian, Staud, Frantisek

Journal:

Year:

2016

Language:

english

File:

PDF, 806 KB

english, 2016

35

Placental passage of olomoucine II, but not purvalanol A, is affected by p-glycoprotein (ABCB1), breast cancer resistance protein (ABCG2) and multidrug resistance-associated proteins (ABCCs)

Hofman, Jakub, Kučera, Radim, Neumanova, Zuzana, Klimes, Jiri, Ceckova, Martina, Staud, Frantisek

Journal:

Year:

2016

Language:

english

File:

PDF, 794 KB

english, 2016

36

Variation of Drug Kinetics in Pregnancy

Pavek, Petr, Ceckova, Martina, Staud, Frantisek

Journal:

Current Drug Metabolism

Year:

2009

Language:

english

File:

PDF, 163 KB

english, 2009

37

Interactions of tenofovir and tenofovir disoproxil fumarate with drug efflux transporters ABCB1, ABCG2, and ABCC2; role in transport across the placenta

Neumanova, Zuzana, Cerveny, Lukas, Ceckova, Martina, Staud, Frantisek

Journal:

Year:

2014

Language:

english

File:

PDF, 387 KB

english, 2014

38

P-glycoprotein function and expression during obstructive cholestasis in rats

Micuda, Stanislav, Brcakova, Eva, Fuksa, Leos, Cermanova, Jolana, Osterreicher, Jan, Hroch, Milos, Mokry, Jaroslav, Pejchal, Jaroslav, Martinkova, Jirina, Staud, Frantisek

Journal:

European Journal of Gastroenterology & Hepatology

Year:

2008

Language:

english

File:

PDF, 250 KB

english, 2008

39

Long-term administration of tenofovir or emtricitabine to pregnant rats; effect on Abcb1a , Abcb1b and Abcg2 expression in the placenta and in maternal and fetal organs

Cerveny, Lukas, Neumanova, Zuzana, Karbanova, Sara, Havlova, Ivana, Staud, Frantisek

Journal:

Journal of Pharmacy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 455 KB

english, 2016

40

Role of ABC and Solute Carrier Transporters in the Placental Transport of Lamivudine

Ceckova, Martina, Reznicek, Josef, Ptackova, Zuzana, Cerveny, Lukas, Müller, Fabian, Kacerovsky, Marian, Fromm, Martin F., Glazier, Jocelyn D., Staud, Frantisek

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 1.30 MB

english, 2016

41

Etravirine inhibits ABCG2 drug transporter and affects transplacental passage of tenofovir disoproxil fumarate

Reznicek, Josef, Ceckova, Martina, Tupova, Lenka, Staud, Frantisek

Journal:

Year:

2016

Language:

english

File:

PDF, 934 KB

english, 2016

42

Pharmacokinetic Evaluation of Biodistribution Data Obtained with Radiolabeled Proteins in Mice.

NISHIKAWA, Makiya, STAUD, Frantisek, TAKEMURA, Shigeo, TAKAKURA, Yoshinobu, HASHIDA, Mitsuru

Journal:

Biological & Pharmaceutical Bulletin

Year:

1999

File:

PDF, 769 KB

1999

43

Alteration of Methotrexate Biliary and Renal Elimination during Extrahepatic and Intrahepatic Cholestasis in Rats

Brcakova, Eva, Fuksa, Leos, Cermanova, Jolana, Kolouchova, Gabriela, Hroch, Milos, Hirsova, Petra, Martinkova, Jirina, Staud, Frantisek, Micuda, Stanislav

Journal:

Biological & Pharmaceutical Bulletin

Year:

2009

Language:

english

File:

PDF, 691 KB

english, 2009

44

MDR1 and BCRP transporter-mediated drug-drug interaction between rilpivirine and abacavir; effect on intestinal absorption

Reznicek, Josef, Ceckova, Martina, Ptackova, Zuzana, Martinec, Ondrej, Tupova, Lenka, Cerveny, Lukas, Staud, Frantisek

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2017

Language:

english

File:

PDF, 807 KB

english, 2017

45

Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro

Sorf, Ales, Hofman, Jakub, Kučera, Radim, Staud, Frantisek, Ceckova, Martina

Journal:

Biochemical Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.09 MB

english, 2018

46

LC-MS/MS method for determination of cyclin-dependent kinase inhibitors, BP-14 and BP-20, and its application in pharmacokinetic study in rat

Široká, Jitka, Čečková, Martina, Urbánek, Lubor, Kryštof, Vladimír, Gucký, Tomáš, Hofman, Jakub, Strnad, Miroslav, Štaud, František

Journal:

Journal of Chromatography B

Year:

2018

Language:

english

File:

PDF, 972 KB

english, 2018

47

Expression of Concentrative Nucleoside Transporters ( SLC28A ) in the Human Placenta: Effects of Gestation Age and Prototype Differentiation-Affecting Agents

Jiraskova, Lucie, Cerveny, Lukas, Karbanova, Sara, Ptackova, Zuzana, Staud, Frantisek

Journal:

Molecular Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.09 MB

english, 2018

48

Interactions of protease inhibitors atazanavir and ritonavir with ABCB1, ABCG2, and ABCC2 transporters: Effect on transplacental disposition in rats

Cerveny, Lukas, Ptackova, Zuzana, Durisova, Marketa, Staud, Frantisek

Journal:

Reproductive Toxicology

Year:

2018

Language:

english

File:

PDF, 599 KB

english, 2018

49

Olomoucine II, but Not Purvalanol A, Is Transported by Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1)

Hofman, Jakub, Kučera, Radim, Cihalova, Daniela, Klimes, Jiri, Ceckova, Martina, Staud, Frantisek, van Veen, Hendrik W.

Journal:

Year:

2013

Language:

english

File:

PDF, 977 KB

english, 2013

50

Purvalanol A, Olomoucine II and Roscovitine Inhibit ABCB1 Transporter and Synergistically Potentiate Cytotoxic Effects of Daunorubicin In Vitro

Cihalova, Daniela, Hofman, Jakub, Ceckova, Martina, Staud, Frantisek, Multhoff, Gabriele

Journal:

Year:

2013

Language:

english

File:

PDF, 839 KB

english, 2013

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